Recombinant Human RBM10, His-tagged

• Cat.No.: RBM10-26514TH
• Product Overview: Recombinant fragment, corresponding to amino acids 306-852 of Human RBM10 with an N terminal His tag. Predicted MWt: 61 kDa

Specification

• Description: This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 105 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: GSKRDMASNEGSRISAASVASTAIA AAQWAISQASQGGEG TWATSEEPPVDYSYYQQDEGYGNSQ GTESSLYAHGYLK GTKGPGITGTKGDPTGAGPEASLEP GADSVSMQAFSRA QPGAAPGIYQQSAEASSSQGTAANS QSYTIMSPAVLKSEL QSPTHPSSALPPATSPTAQESYSQY PVPDVSTYQYDET SGYYYDPQTGLYYDPNSQYYYNAQS QQYLYWDGERRTY VPALEQSADGHKETGAPSKEGKEKK EKHKTKTAQQIAKDMERWARSLNKQ KENFKNSFQPISSLRDDERRESATA DAG YAILEKKGALAERQHTSMDLPKLAS DDRPSPPRGLVAA YSGESDSEEEQERGGPEREEKLTDW QKLACLLCRRQFP SKEALIRHQQLSGLHKQNLEIHRRA HLSENELEALEKNDM EQMKYRDRAAERREKYGIPEPPEPK RRKYGGISTASVD FEQPTRDGLGSDNIGSRMLQAMGWK EGSGLGRKKQGIV TPIEAQTRVRGSGLGARGSSYGVTS TESYKETLHKTMVTRFNEAQ

Gene Information

• Gene Name: RBM10 RNA binding motif protein 10 [ Homo sapiens ]
• Official Symbol: RBM10
• Synonyms: RBM10; RNA binding motif protein 10; RNA-binding protein 10; DXS8237E; GPATC9; GPATCH9; KIAA0122; ZRANB5
• Gene ID: 8241
• mRNA Refseq: NM_001204466
• Protein Refseq: NP_001191395
• MIM: 300080
• Uniprot ID: P98175
• Chromosome Location: Xp11.3
• Function: RNA binding; metal ion binding; nucleotide binding; zinc ion binding