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Recombinant Mouse Intercellular Adhesion Molecule 2

Cat. No. : Icam2-1746M
Description : Intercellular adhesion molecule 2 (ICAM2), also known as CD102 (Cluster of Differentiation 102), is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
Molecular Weight : The predicted molecular weight of Recombinant Mouse ICAM-2 is Mr 49.5 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 75-80 kDa.
Source : NSO Cells.
State Of Matter : Lyophilized.
Purity : >95% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°Cto -70°C. After aseptic reconstitution, this protein may be stored at 2°Cto 8°Cfor one month or at -20°Cto -70°Cin a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.
Gene Name : Icam2 intercellular adhesion molecule 2 [ Mus musculus ]
Synonyms : Icam2; intercellular adhesion molecule 2; CD102; Ly-60; Icam-2; OTTMUSP00000003460; OTTMUSP00000003463
Gene ID : 15896
mRNA Refseq : NM_010494
Protein Refseq : NP_034624
UniProt ID : P35330
Chromosome Location : 11 E1; 11 63.0 cM
Pathway : Cell adhesion molecules (CAMs); Natural killer cell mediated cytotoxicity
Function : protein binding

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