Recombinant Human RBX1
Cat.No. : | RBX1-31333TH |
Product Overview : | Recombinant full lengthhuman ROC1 protein, 12 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This locus encodes a RING finger-like domain-containing protein. The encoded protein interacts with cullin proteins and likely plays a role in ubiquitination processes necessary for cell cycle progression. This protein may also affect protein turnover. Related pseudogenes exist on chromosomes 2 and 5. |
Source : | E. coli |
Tissue specificity : | Widely expressed. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the RING-box family.Contains 1 RING-type zinc finger. |
Gene Name : | RBX1 ring-box 1, E3 ubiquitin protein ligase [ Homo sapiens ] |
Official Symbol : | RBX1 |
Synonyms : | RBX1; ring-box 1, E3 ubiquitin protein ligase; ring box 1; E3 ubiquitin-protein ligase RBX1; BA554C12.1; regulator of cullins 1; RNF75; ROC1; |
Gene ID : | 9978 |
mRNA Refseq : | NM_014248 |
Protein Refseq : | NP_055063 |
MIM : | 603814 |
Uniprot ID : | P62877 |
Chromosome Location : | 22q13.2 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem; |
Function : | NEDD8 ligase activity; ligase activity; metal ion binding; protein binding; contributes_to ubiquitin-protein ligase activity; |
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◆ Lysates | ||
RBX1-2450HCL | Recombinant Human RBX1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionIt facilitates the attachment of ubiquitin, directing proteins to the proteasome for breakdown.
Targeting RBX1 offers potential for treating diseases with dysregulated protein turnover, including cancer.
Altered RBX1 activity is associated with cancer progression, influencing cell proliferation and survival.
RBX1 plays a role in cell cycle control by regulating the degradation of key cycle-related proteins.
Genetic mutations in RBX1 can lead to disruptions in protein turnover, affecting various cellular functions.
RBX1, a RING-finger protein, is crucial for tagging proteins with ubiquitin, marking them for degradation.
RBX1 works with other ubiquitin-proteasome system components, orchestrating protein degradation.
Customer Reviews (3)
Write a reviewEfficiency and precision, vital for research quality.
Critical for decision-making, accelerates research productivity.
Enhances research credibility, a cornerstone of our research.
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