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Recombinant Human RCVRN

Cat.No. : RCVRN-31310TH
Product Overview : Recombinant full length protein, corresponding to amino acids 1-200 of Human Recoverin
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy.
Source : E. coli
Tissue specificity : Retina and pineal gland.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, 2mM Magnesium chloride, 1mM EDTA, pH 8.0
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids : MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDTDPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKNEVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANKEILRLIQFEP QKVKEKMKNA
Sequence Similarities : Belongs to the recoverin family.Contains 4 EF-hand domains.
Gene Name : RCVRN recoverin [ Homo sapiens ]
Official Symbol : RCVRN
Synonyms : RCVRN; recoverin; RCV1;
Gene ID : 5957
mRNA Refseq : NM_002903
Protein Refseq : NP_002894
MIM : 179618
Uniprot ID : P35243
Chromosome Location : 17p13.1
Pathway : Phototransduction, organism-specific biosystem; Phototransduction, conserved biosystem;
Function : calcium ion binding; calcium sensitive guanylate cyclase activator activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any specific populations that may benefit more from RCVRN-targeted therapies? 03/02/2022

Individuals with genetic mutations affecting RCVRN and those with early-stage retinal diseases may potentially benefit more from targeted therapies.

How does the expression of RCVRN change with age, and does this have implications for age-related vision disorders? 10/29/2021

The expression of RCVRN may change with age, and understanding these changes can provide insights into age-related vision disorders.

How is the level of RCVRN expression correlated with the progression of certain retinal disorders? 01/22/2021

Changes in RCVRN expression levels may correlate with the progression of retinal disorders, serving as a potential indicator of disease severity.

Are there ongoing clinical trials exploring the use of RCVRN-based therapies? 02/11/2017

Some clinical trials are investigating the safety and efficacy of gene therapies targeting the RCVRN gene for treating specific eye conditions.

How might the manipulation of RCVRN expression offer therapeutic benefits for patients with vision impairments? 03/04/2016

Modulating RCVRN expression could potentially restore or enhance photoreceptor function, providing therapeutic benefits for vision-impaired individuals.

Customer Reviews (3)

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Reviews
02/16/2020

    Whether investigating metabolic pathways, studying enzymatic activity, or exploring drug targets, this protein offers versatility and reliability, allowing for accurate and meaningful data collection.

    05/29/2018

      In addition to the remarkable protein quality, the manufacturer provides excellent technical support, proving to be a valuable resource when troubleshooting experimental challenges.

      06/24/2016

        Incorporating this protein into scientific investigations undoubtedly enhances the reliability and effectiveness of research endeavors.

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