Recombinant Human RCVRN
Cat.No. : | RCVRN-31310TH |
Product Overview : | Recombinant full length protein, corresponding to amino acids 1-200 of Human Recoverin |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the recoverin family of neuronal calcium sensors. The encoded protein contains three calcium-binding EF-hand domains and may prolong the termination of the phototransduction cascade in the retina by blocking the phosphorylation of photo-activated rhodopsin. Recoverin may be the antigen responsible for cancer-associated retinopathy. |
Source : | E. coli |
Tissue specificity : | Retina and pineal gland. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 20mM Tris, 2mM Magnesium chloride, 1mM EDTA, pH 8.0 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
Sequences of amino acids : | MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDTDPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKNEVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANKEILRLIQFEP QKVKEKMKNA |
Sequence Similarities : | Belongs to the recoverin family.Contains 4 EF-hand domains. |
Gene Name : | RCVRN recoverin [ Homo sapiens ] |
Official Symbol : | RCVRN |
Synonyms : | RCVRN; recoverin; RCV1; |
Gene ID : | 5957 |
mRNA Refseq : | NM_002903 |
Protein Refseq : | NP_002894 |
MIM : | 179618 |
Uniprot ID : | P35243 |
Chromosome Location : | 17p13.1 |
Pathway : | Phototransduction, organism-specific biosystem; Phototransduction, conserved biosystem; |
Function : | calcium ion binding; calcium sensitive guanylate cyclase activator activity; |
Products Types
◆ Recombinant Protein | ||
RCVRN-1870H | Recombinant Human RCVRN Protein, His (Fc)-Avi-tagged | +Inquiry |
RCVRN-3652R | Recombinant Rhesus Macaque RCVRN Protein, His (Fc)-Avi-tagged | +Inquiry |
Rcvrn-5441M | Recombinant Mouse Rcvrn Protein, Myc/DDK-tagged | +Inquiry |
RCVRN-2765H | Recombinant Human RCVRN Protein (2-200 aa), His-Myc-tagged | +Inquiry |
RCVRN-250H | Recombinant Human RCVRN Protein, His-tagged | +Inquiry |
◆ Lysates | ||
RCVRN-2442HCL | Recombinant Human RCVRN 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionIndividuals with genetic mutations affecting RCVRN and those with early-stage retinal diseases may potentially benefit more from targeted therapies.
The expression of RCVRN may change with age, and understanding these changes can provide insights into age-related vision disorders.
Changes in RCVRN expression levels may correlate with the progression of retinal disorders, serving as a potential indicator of disease severity.
Some clinical trials are investigating the safety and efficacy of gene therapies targeting the RCVRN gene for treating specific eye conditions.
Modulating RCVRN expression could potentially restore or enhance photoreceptor function, providing therapeutic benefits for vision-impaired individuals.
Customer Reviews (3)
Write a reviewWhether investigating metabolic pathways, studying enzymatic activity, or exploring drug targets, this protein offers versatility and reliability, allowing for accurate and meaningful data collection.
In addition to the remarkable protein quality, the manufacturer provides excellent technical support, proving to be a valuable resource when troubleshooting experimental challenges.
Incorporating this protein into scientific investigations undoubtedly enhances the reliability and effectiveness of research endeavors.
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