Recombinant Human RDX

• Cat.No.: RDX-29366TH
• Product Overview: Recombinant full length Human Radixin with N terminal proprietary tag; Predicted MWt 90.24 kDa including the tag.

Specification

• Description: Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses.
• Protein length: 583 amino acids
• Molecular Weight: 90.240kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MPKPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLR EVWFFGLQYVDSKGYSTWLKLNKKVTQQDVKKENPLQFKF RAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPE TAVLLASYAVQAKYGDYNKEIHKPGYLANDRLLPQRVLEQ HKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKIAQDLEM YGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGF PWSEIRNISFNDKKFVIKPIDKKAPDFVFYAPRLRINKRI LALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLER AQLENEKEKREIAEKEKERIEREKEELMERLKQIEEQTIK AQKELEEQTRKALELDQERKRAKEEAERLEKERRAAEEAK SAIAKQAADQMKNQEQLAAELAEFTAKIALLEEAKKKKEE EATEWQHKAFAAQEDLEKTKEELKTVMSAPPPPPPPPVIP PTENEHDEHDENNAEASAELSNEGVMNHRSEEERVTETQK NERVKKQLQALSSELAQARDETKKTQNDVLHAENVKAGRD KYKTLRQIRQGNTKQRIDEFEAM
• Sequence Similarities: Contains 1 FERM domain.

Gene Information

• Gene Name: RDX radixin [ Homo sapiens ]
• Official Symbol: RDX
• Synonyms: RDX; radixin; deafness, autosomal recessive 24 , DFNB24
• Gene ID: 5962
• mRNA Refseq: NM_002906
• Protein Refseq: NP_002897
• MIM: 179410
• Uniprot ID: P35241
• Chromosome Location: 11q23
• Pathway: Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Recycling pathway of L1, organism-specific biosystem; Regulation of Actin Cytoskeleton, organism-specific biosystem
• Function: actin binding; protein binding