Recombinant Human REG3A, His-tagged

• Cat.No.: REG3A-30487TH
• Product Overview: Recombinant full length protein, corresponding to amino acids 27-175 of Human Reg3a produced with an N-terminalHis Tag; 149aa with an 16 additional amino acid residues. 18 kDa.

Specification

• Description: This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. Alternate splicing results in multiple transcript variants that encode the same protein.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Constitutively expressed in intestine. Low expression is found in healthy pancreas. Overexpressed during the acute phase of pancreatitis and in some patients with chronic pancreatitis.
• Form: Lyophilised:Add 0.2 ml of 0.1M Acetate buffer pH-4 and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solu
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 0.05M Acetate buffer, pH4
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MRGSHHHHHH GMASHMEEPQ RELPSARIRC PKGSKAYGSH CYALFLSPKS WTDADLACQK RPSGNLVSVL SGAEGSFVSS LVKSIGNSYS YVWIGLHDPT QGTEPNGEGW EWSSSDVMNY FAWERNPSTI SSPGHCASLS RSTAFLRWKD YNCNVRLPYV CKFTD
• Sequence Similarities: Contains 1 C-type lectin domain.

Gene Information

• Gene Name: REG3A regenerating islet-derived 3 alpha [ Homo sapiens ]
• Official Symbol: REG3A
• Synonyms: REG3A; regenerating islet-derived 3 alpha; pancreatitis associated protein , PAP; regenerating islet-derived protein 3-alpha; HIP; PAP1; PBCGF; REG III; REG3
• Gene ID: 5068
• mRNA Refseq: NM_002580
• Protein Refseq: NP_002571
• MIM: 167805
• Uniprot ID: Q06141
• Chromosome Location: 2p12
• Function: binding; sugar binding