"RLN2" Related Products

Recombinant Human RLN2

Cat.No.: RLN2-30491TH
Product Overview: Full length human recombinant Relaxin 2.
Description: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non-allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
Source: E. coli
Form: Lyophilised:Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Purity: >95% by SDS-PAGE
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Sequences of amino acids: A-Chain: QLYSALANKC CHVGCTKRSL ARFCB-Chain: DSWMEEVIKL CGRELVRAQI AICGMSTWS
Gene Name: RLN2 relaxin 2 [ Homo sapiens ]
Official Symbol: RLN2
Synonyms: RLN2; relaxin 2; relaxin 2 (H2); prorelaxin H2; bA12D24.1.1; bA12D24.1.2; H2; relaxin H2; relaxin; ovarian; of pregnancy; RLXH2;
Gene ID: 6019
mRNA Refseq: NM_005059
Protein Refseq: NP_005050
MIM: 179740
Uniprot ID: P04090
Chromosome Location: 9pter-q12
Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Peptide ligand-binding receptors, organism-specific biosystem;
Function: hormone activity;

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