Recombinant Human RND1, His-tagged

• Cat.No.: RND1-31330TH
• Product Overview: Recombinant fragment of Human RND1 (amino acids 1-200) with an N terminal His tag; 220aa, 24.5kDa inclusive of tag.

Specification

• Description: Members of the Rho GTPase family, such as RND1, regulate the organization of the actin cytoskeleton in response to extracellular growth factors (Nobes et al.
• Protein length: 200 amino acids
• Conjugation: HIS
• Molecular Weight: 24.500kDa
• Source: E. coli
• Tissue specificity: Mostly expressed in brain and liver.
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 30% Glycerol, 0.58% Sodium chloride, 0.02% DTT
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSHSPYYDNVRPL CYSDSDAVLL CFDISRPETV DSALKKWRTE ILDYCPSTRV LLIGCKTDLR TDLSTLMELS HQKQAPISYE QGCAIAKQLG MKERRAPQPV VARCKLVLVG DVQCGKTAML QVLAKDCYPE TYVPTVFENY TACLETEEQR VELSLWDTSGAEIYLEGSAF TSEKSIHSIF RTASMLCLNK PSPLPQKSPV
• Sequence Similarities: Belongs to the small GTPase superfamily. Rho family.

Gene Information

• Gene Name: RND1 Rho family GTPase 1 [ Homo sapiens ]
• Official Symbol: RND1
• Synonyms: RND1; Rho family GTPase 1; rho-related GTP-binding protein Rho6; ARHS; ras homolog gene family; member S; Rho6; RHOS
• Gene ID: 27289
• mRNA Refseq: NM_014470
• Protein Refseq: NP_055285
• MIM: 609038
• Uniprot ID: Q92730
• Chromosome Location: 12q12
• Pathway: Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion, organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding; protein binding; receptor binding