Recombinant Human RPA1, His-tagged

• Cat.No.: RPA1-31145TH
• Product Overview: Recombinant fragment, corresponding to amino acids 257-616 of Human RPA70 with N terminal His tag; Predicted MWt 42 kDa.

Specification

• Description: Replication protein A 70 kDa DNA-binding subunit is a protein that in humans is encoded by the RPA1 gene.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 78 μl distilled water.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: FSKGTLKIANKQFTAVKNDYEMTFNNETSVMPCEDDHHLP TVQFDFTGIDDLENKSKDSLVDIIGICKSYEDATKITV RSNNREVAKRNIYLMDTSGKVVTATLWGEDADKFDGSR QPVLAIKGARVSDFGGRSLSVLSSSTIIANPDIPEAYK LRGWFDAEGQALDGVSISDLKSGGVGGSNTNWKTLYEVKS ENLGQGDKPDYFSSVATVVYLRKENCMYQACPTQDCNK KVIDQQNGLYRCEKCDTEFPNFKYRMILSVNIADFQEN QWVTCFQESAEAILGQNAAYLGELKDKNEQAFEEVFQN ANFRSFIFRVRVKVETYNDESRIKATVMDVKPVDYREYGR RLVMSIRRSALM

Gene Information

• Gene Name: RPA1 replication protein A1, 70kDa [ Homo sapiens ]
• Official Symbol: RPA1
• Synonyms: RPA1; replication protein A1, 70kDa; replication protein A1 (70kD); replication protein A 70 kDa DNA-binding subunit; HSSB; REPA1; RF A; RP A; RPA70
• Gene ID: 6117
• mRNA Refseq: NM_002945
• Protein Refseq: NP_002936
• MIM: 179835
• Uniprot ID: P27694
• Chromosome Location: 17p13.3
• Pathway: Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; Assembly of the RAD51-ssDNA nucleoprotein complex, organism-specific biosystem; Cell Cycle Checkpoints, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem
• Function: DNA binding; metal ion binding; protein binding; single-stranded DNA binding