"RPS6KB2" Related Products

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Recombinant Human RPS6KB2

Cat.No.: RPS6KB2-30578TH
Product Overview: Recombinant full length Human P70 S6 Kinase beta with N-terminal proprietary tag expressed by Baculovirus in Sf9 insect cells, MWt 85kDa.
Description: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain.
Gene Name: RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [ Homo sapiens ]
Official Symbol: RPS6KB2
Synonyms: RPS6KB2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase beta-2; KLS; P70 BETA; p70S6Kb; STK14B;
Gene ID: 6199
mRNA Refseq: NM_003952
Protein Refseq: NP_003943
MIM: 608939
Uniprot ID: Q9UBS0
Chromosome Location: 11q13.1
Pathway: AKT phosphorylates targets in the nucleus, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem;
Function: ATP binding; nucleotide binding; peptide binding; protein kinase activity; protein serine/threonine kinase activity;

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