Recombinant Human RPS6KB2
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Cat.No. : | RPS6KB2-30618TH |
Product Overview : | Recombinant full-length Human P70 S6 Kinase beta was expressed by baculovirus in Sf9 insect cells using an N-terminal proprietary tag. |
Description : | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. |
Biological activity : | Specific activity: 107nmol/min/mg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 1 protein kinase domain. |
Gene Name : | RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 [ Homo sapiens ] |
Official Symbol : | RPS6KB2 |
Synonyms : | RPS6KB2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; ribosomal protein S6 kinase, 70kD, polypeptide 2; ribosomal protein S6 kinase beta-2; KLS; P70 BETA; p70S6Kb; STK14B; |
Gene ID : | 6199 |
mRNA Refseq : | NM_003952 |
Protein Refseq : | NP_003943 |
MIM : | 608939 |
Uniprot ID : | Q9UBS0 |
Chromosome Location : | 11q13.1 |
Pathway : | AKT phosphorylates targets in the nucleus, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Downstream signal transduction, organism-specific biosystem; |
Function : | ATP binding; nucleotide binding; peptide binding; protein kinase activity; protein serine/threonine kinase activity; |
◆ Recombinant Protein
Rps6kb2-5614M | Recombinant Mouse Rps6kb2 Protein, Myc/DDK-tagged | +Inquiry |
RPS6KB2-360H | Recombinant Human RPS6KB2 protein, His/MBP-tagged | +Inquiry |
RPS6KB2-30578TH | Recombinant Human RPS6KB2 | +Inquiry |
RPS6KB2-1935H | Recombinant Human RPS6KB2 protein, His & GST-tagged | +Inquiry |
RPS6KB2-5193H | Recombinant Human RPS6KB2 protein, GST-tagged | +Inquiry |
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◆ Lysates
RPS6KB2-2158HCL | Recombinant Human RPS6KB2 293 Cell Lysate | +Inquiry |
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RPS14 RPS27A RPS3 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA5 RPS6KA6 RPS6KB1 RPS6KB2 RPS6 RPS15 RPS17 RPS19 RPS2 RPS23 RPS27 RPS5 RPS7 RPS6KA4 RPS11 RPS20 RPS28 RPS29 RPS4X RPS6KC1 RPS8 RPS9 RPS24 RPS13 RPS26 RPS27L RPS18 RPS19BP1 RPS21 RPS25 RPS6KL1 RPS4Y1 RPS3A RPS15A RPS10 RPS12 Rps16 RPS17L
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