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Recombinant Mouse Noggin

Cat. No. : Nog-1770M
Description : Noggin is a secreted glycoprotein predominantly expressed by the dorsal mesoderm during embryogenesis that inhibits TGF-β signal transduction by binding to TGF-β family ligands and preventing them from binding to their corresponding receptors.
Source : NSO Cells.
Molecular Weight : The predicted molecular weight of Recombinant Mouse Nog is Mr 26 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 30 - 35 kDa.
State Of Matter : Lyophilized.
Formulation : This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Purity : >90% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name : Nog noggin [ Mus musculus ]
Synonyms : Nog; noggin; OTTMUSP00000001311
Gene ID : 18121
mRNA Refseq : NM_008711
Protein Refseq : NP_032737
UniProt ID : P97466
Chromosome Location : 11 C; 11 50.5 cM
Pathway : TGF-beta signaling pathway

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