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Recombinant Mouse Noggin

Cat. No.: Nog-1770M
Description: Noggin is a secreted glycoprotein predominantly expressed by the dorsal mesoderm during embryogenesis that inhibits TGF-β signal transduction by binding to TGF-β family ligands and preventing them from binding to their corresponding receptors.
Source: NSO Cells.
Molecular Weight: The predicted molecular weight of Recombinant Mouse Nog is Mr 26 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 30 - 35 kDa.
State Of Matter: Lyophilized.
Formulation: This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Purity: >90% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: Nog noggin [ Mus musculus ]
Synonyms: Nog; noggin; OTTMUSP00000001311
Gene ID: 18121
mRNA Refseq: NM_008711
Protein Refseq: NP_032737
UniProt ID: P97466
Chromosome Location: 11 C; 11 50.5 cM
Pathway: TGF-beta signaling pathway

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