Recombinant Human SOD1
Cat.No. : | SOD1-30341TH |
Product Overview : | Recombinant full length Human Superoxide Dismutase 1 with N-terminal proprietary tag; amino acids 1-54, MW 45kDa. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. |
Source : | E. coli |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the Cu-Zn superoxide dismutase family. |
Gene Name : | SOD1 superoxide dismutase 1, soluble [ Homo sapiens ] |
Official Symbol : | SOD1 |
Synonyms : | SOD1; superoxide dismutase 1, soluble; ALS, ALS1, amyotrophic lateral sclerosis 1 (adult); superoxide dismutase [Cu-Zn]; IPOA; |
Gene ID : | 6647 |
mRNA Refseq : | NM_000454 |
Protein Refseq : | NP_000445 |
MIM : | 147450 |
Uniprot ID : | P00441 |
Chromosome Location : | 21q22.11 |
Pathway : | Amyotrophic lateral sclerosis (ALS), organism-specific biosystem; Amyotrophic lateral sclerosis (ALS), conserved biosystem; FOXA1 transcription factor network, organism-specific biosystem; Folate Metabolism, organism-specific biosystem; Hemostasis, organism-specific biosystem; |
Function : | chaperone binding; copper ion binding; metal ion binding; oxidoreductase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
SOD1-8568M | Recombinant Mouse SOD1 Protein, His (Fc)-Avi-tagged | +Inquiry |
SOD1-05H | Active Recombinant Human Superoxide Dismutase 1 / SOD1 protein, Tag Free | +Inquiry |
SOD1-070H | Recombinant Human SOD1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
SOD1-1158H | Recombinant Human SOD1 Protein, MYC/DDK-tagged | +Inquiry |
SOD1-956C | Recombinant Cynomolgus SOD1 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
SOD1-101B | Active Native Bovine SOD | +Inquiry |
SOD1-102B | Active Native Bovine SOD, modified | +Inquiry |
CED026 | Active Bovine Superoxide Dismutase (SOD), High Purity >95% | +Inquiry |
◆ Lysates | ||
SOD1-1576HCL | Recombinant Human SOD1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionTherapeutic strategies may involve modulating SOD1 activity or expression to mitigate oxidative stress-related damage.
SOD1 acts as an antioxidant, converting superoxide radicals to hydrogen peroxide and oxygen.
Mutations in SOD1 can result in loss or gain of function, contributing to disease development.
SOD1 mutations are implicated in Amyotrophic Lateral Sclerosis (ALS), leading to neurodegeneration.
SOD1 is primarily located in the cytoplasm and mitochondrial intermembrane space.
It helps maintain cellular redox balance, protecting cells from oxidative damage.
It plays a crucial role in cellular defense against oxidative stress.
Customer Reviews (3)
Write a reviewWorked perfectly, no problems.
Quick delivery, fantastic product.
Reliable results every time.
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