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Recombinant Human SOX9

Cat.No. : SOX9-30696TH
Product Overview : Recombinant fragment, corresponding to amino acids 1-150 of Human SOX9 with proprietary tag, 150 amino acids, 43kDa.
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  • Gene Information
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Description : The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Source : E. coli
Form : Liquid
Storage buffer : Preservative: NoneConstituents: 20% Glycerol, 50mM Tris acetate, 1mM EDTA, pH 7.5
Storage : Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Contains 1 HMG box DNA-binding domain.
Gene Name : SOX9 SRY (sex determining region Y)-box 9 [ Homo sapiens ]
Official Symbol : SOX9
Synonyms : SOX9; SRY (sex determining region Y)-box 9; campomelic dysplasia, autosomal sex reversal , CMD1, CMPD1; transcription factor SOX-9; SRA1;
Gene ID : 6662
mRNA Refseq : NM_000346
Protein Refseq : NP_000337
MIM : 608160
Uniprot ID : P48436
Chromosome Location : 17q23
Pathway : Endochondral Ossification, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem;
Function : RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; beta-catenin binding; chromatin binding; core promoter sequence-specific DNA binding; enhancer bi;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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