Recombinant Human SPR, His-tagged
Cat.No. : | SPR-30401TH |
Product Overview : | Recombinant full length Human SPR fused to His-tag at N-terminus; amino acids 1-261 , 30.2kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 20mM Tris HCl, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MEGGLGRAVC LLTGASRGFG RTLAPLLASL LSPGSVLVLS ARNDEALRQL EAELGAERSG LRVVRVPADL GAEAGLQQLL GALRELPRPK GLQRLLLINN AGSLGDVSKG FVDLSDSTQV NNYWALNLTS MLCLTSSVLK AFPDSPGLNR TVVNISSLCA LQPFKGWALY CAGKAARDML FQVLALEEPN VRVLNYAPGP LDTDMQQLAR ETSVDPDMRK GLQELKAKGK LVDCKVSAQK LLSLLEKDEF KSGAHVDFYD K |
Sequence Similarities : | Belongs to the sepiapterin reductase family. |
Gene Name : | SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) [ Homo sapiens ] |
Official Symbol : | SPR |
Synonyms : | SPR; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase); sepiapterin reductase; SDR38C1; short chain dehydrogenase/reductase family 38C; member 1; |
Gene ID : | 6697 |
mRNA Refseq : | NM_003124 |
Protein Refseq : | NP_003115 |
MIM : | 182125 |
Uniprot ID : | P35270 |
Chromosome Location : | 2p14-p12 |
Pathway : | Folate biosynthesis, organism-specific biosystem; Folate biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nitric oxide, organism-specific biosystem; |
Function : | NADP binding; aldo-keto reductase (NADP) activity; oxidoreductase activity; sepiapterin reductase activity; |
Products Types
◆ Recombinant Protein | ||
Spr-6107M | Recombinant Mouse Spr Protein, Myc/DDK-tagged | +Inquiry |
SPR-4262R | Recombinant Rhesus Macaque SPR Protein, His (Fc)-Avi-tagged | +Inquiry |
Spr-682M | Recombinant Mouse Spr Protein, His-tagged | +Inquiry |
SPR-0243H | Recombinant Human SPR Protein (M1-K261), Tag Free | +Inquiry |
SPR-0242H | Recombinant Human SPR Protein (M1-K261), His tagged | +Inquiry |
◆ Lysates | ||
SPR-1499HCL | Recombinant Human SPR 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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