Recombinant Human SRR, His-tagged

• Cat.No.: SRR-31354TH
• Product Overview: Recombinant full length Human Serine racemase with N terminal His tag; 364 amino acids with tag, Predicted MWt 39.1 kDa.

Specification

• Description: catalyzes the conversion of L-serine to D-serine
• Protein length: 340 amino acids
• Conjugation: HIS
• Molecular Weight: 39.100kDa inclusive of tags
• Source: E. coli
• Tissue specificity: Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: pH: 8.00Constituents:0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMGSHMCAQYCISFADVEKAH INIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFK IRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAK LEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRE NVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL VDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADD CYQSKLKGKLMPNLYPPETIADGVKSSIGLNTWPIIRDLV DDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQ HFQTVSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQ SVSV
• Sequence Similarities: Belongs to the serine/threonine dehydratase family.

Gene Information

• Gene Name: SRR serine racemase [ Homo sapiens ]
• Official Symbol: SRR
• Synonyms: SRR; serine racemase; ILV1; ISO1
• Gene ID: 63826
• mRNA Refseq: NM_021947
• Protein Refseq: NP_068766
• MIM: 606477
• Uniprot ID: Q9GZT4
• Chromosome Location: 17p13
• Pathway: Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem
• Function: ATP binding; ATP binding; D-serine ammonia-lyase activity; L-serine ammonia-lyase activity; PDZ domain binding