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Recombinant Human STUB1

Cat.No.: STUB1-30459TH
Product Overview: Recombinant full length protein, corresponding to amino acids 1-303 of Human STUB1, 34.8kDa.
Description: STUB1, or CHIP, is a ubiquitin ligase/cochaperone that participates in protein quality control by targeting a broad range of chaperone protein substrates for degradation (Min et al.
Source: E. coli
Tissue specificity: Highly expressed in skeletal muscle, heart, pancreas, brain and placenta. Detected in kidney, liver and lung.
Form: Liquid
Purity: >90% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 5mM DTT, 20mM Tris HCl, pH 7.5
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids: MKGKEEKEGG ARLGAGGGSP EKSPSAQELK EQGNRLFVGR KYPEAAACYG RAITRNPLVA VYYTNRALCY LKMQQHEQAL ADCRRALELD GQSVKAHFFL GQCQLEMESY DEAIANLQRA YSLAKEQRLN FGDDIPSALR IAKKKRWNSI EERRIHQESE LHSYLSRLIA AERERELEEC QRNHEGDEDD SHVRAQQACI EAKHDKYMAD MDELFSQVDE KRKKRDIPDY LCGKISFELM REPCITPSGI TYDRKDIEEH LQRVGHFDPV TRSPLTQEQL IPNLAMKEVI DAFISENGWV EDY
Sequence Similarities: Contains 3 TPR repeats.Contains 1 U-box domain.
Gene Name: STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase [ Homo sapiens ]
Official Symbol: STUB1
Synonyms: STUB1; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase; STIP1 homology and U box containing protein 1; E3 ubiquitin-protein ligase CHIP; CHIP; HSPABP2; NY CO 7; SDCCAG7; UBOX1;
Gene ID: 10273
mRNA Refseq: NM_005861
Protein Refseq: NP_005852
MIM: 607207
Uniprot ID: Q9UNE7
Chromosome Location: 16p13.3
Pathway: Adaptive Immune System, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem;
Function: Hsp70 protein binding; Hsp90 protein binding; SMAD binding; TPR domain binding; enzyme binding;

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