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Recombinant Human SURF1, His-tagged

Cat.No. : SURF1-31483TH
Product Overview : Recombinant fragment of Human SURF1 fused to a 20 amino acid His Tag at N-terminus, 24.3kDa.
  • Specification
  • Gene Information
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Description : This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Protein length : 194 amino acids
Conjugation : HIS
Molecular Weight : 24.300kDa inclusive of tags
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Constituents:0.32% Tris HCl, 0.58% Sodium chloride, 0.02% DTT, 20% Glycerol
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MQVQRRKWKL NLIAELESRV LAEPVPLPAD PMELKNLEYR PVKVRGCFDH SKELYMMPRT MVDPVREARE GGLISSSTQS GAYVVTPFHC TDLGVTILVN RGFVPRKKVN PETRQKGQIE GEVDLIGMVR LTETRQPFVP ENNPERNHWH YRDLEAMARI TGAEPIFIDA NFQSTVPGGP IGGQTRVTLR NEHLQ
Sequence Similarities : Belongs to the SURF1 family.
Gene Name : SURF1 surfeit 1 [ Homo sapiens ]
Official Symbol : SURF1
Synonyms : SURF1; surfeit 1; surfeit locus protein 1;
Gene ID : 6834
mRNA Refseq : NM_003172
Protein Refseq : NP_003163
MIM : 185620
Uniprot ID : Q15526
Chromosome Location : 9q33-q34
Pathway : Electron Transport Chain, organism-specific biosystem;
Function : cytochrome-c oxidase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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