Recombinant Human TAGLN, His-tagged

• Cat.No.: TAGLN-30925TH
• Product Overview: Recombinant full length Human SM22 alpha with N terminal His tag; 221 amino acids with tag, MWt 24.8kDa.

Specification

• Description: The protein encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.
• Protein length: 201 amino acids
• Conjugation: HIS
• Molecular Weight: 24.800kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHHSSGLVPRGSHMANKG PSYGMSREVQSKIEKKYDEELEERL VEWIIVQCGPDVGRPDRGRLGFQVW LKNGVILSKLVNSLYPDGSKPVKVP ENPPSMVFKQMEQVAQFLKAAEDYG VIKTDMFQTVDLFEGKDMAAVQRTL MALGSLAVTKNDGHYRGDPNWFMKK AQEHKREFTESQLQEGKHVIGLQMG SNRGASQAGMTGYGRPRQIIS
• Sequence Similarities: Belongs to the calponin family.Contains 1 calponin-like repeat.Contains 1 CH (calponin-homology) domain.

Gene Information

• Gene Name: TAGLN transgelin [ Homo sapiens ]
• Official Symbol: TAGLN
• Synonyms: TAGLN; transgelin; DKFZp686P11128; SM22; SM22 alpha; SMCC; TAGLN1; transgelin variant 2; WS3 10
• Gene ID: 6876
• mRNA Refseq: NM_001001522
• Protein Refseq: NP_001001522
• MIM: 600818
• Uniprot ID: Q01995
• Chromosome Location: 11q23.2
• Function: actin binding