Recombinant Rat Prolactin Receptor

• Cat.No.: Prlr-1797R

Specification

• Cat. No.: Prlr-1797R
• Description: Prolactin Receptor (PRLR) is a cytokine receptor superfamily that lacks an intrinsic kinase domain and relies on the cytoplasmic Jak tyrosine kinases to transduce signals. PRLR is required for the signaling and proliferation of prolactin.
• Source: Mammalian cells
• Molecular Weight: The predicted molecular weight of Recombinant Rat PRL is Mr 51 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 67-74 kDa.
• State Of Matter: Lyophilized.
• Purity: >90% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Biological Activity: The biological activity of Rat PRL was determined by Measured by its ability to neutralize the rhProlactin-induced proliferation of the rat lymphoma Nb2-11 treated with 0.5 ng/mL of rhProlactin.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: Prlr prolactin receptor [ Rattus norvegicus ]
• Synonyms: Prlr; prolactin receptor; RATPRLR; MGC105486
• Gene ID: 24684
• mRNA Refseq: NM_001034111
• Protein Refseq: NP_001029283
• UniProt ID: P05710
• Chromosome Location: 2q16
• Pathway: Cytokine-cytokine receptor interaction; Neuroactive ligand-receptor interaction; Jak-STAT signaling pathway
• Function: peptide hormone binding; prolactin receptor activity; protein binding