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Recombinant Human TCEB2

Cat.No. : TCEB2-30816TH
Product Overview : Recombinant full length Human TCEB2 protein , predicted MWt: 13.1 kDa.
  • Specification
  • Gene Information
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Description : This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
Protein length : 118 amino acids
Molecular Weight : 13.100kDa
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : pH: 8.00Constituents:0.32% Tris HCl, 0.02% DTT, 0.02% PMSF, 20% Glycerol
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MDVFLMIRRH KTTIFTDAKE SSTVFELKRI VEGILKRPPD EQRLYKDDQL LDDGKTLGEC GFTSQTARPQ APATVGLAFR ADDTFEALCIEPFSSPPELP DVMKPQDSGS SANEQAVQ
Sequence Similarities : Contains 1 ubiquitin-like domain.
Gene Name : TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) [ Homo sapiens ]
Official Symbol : TCEB2
Synonyms : TCEB2; transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B); transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B); transcription elongation factor B polypeptide 2; SIII;
Gene ID : 6923
mRNA Refseq : NM_007108
Protein Refseq : NP_009039
MIM : 600787
Uniprot ID : Q15370
Chromosome Location : 16p12.3
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem;
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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