Recombinant Human TDGF1, MBP-tagged
Cat.No. : | TDGF1-27822TH |
Product Overview : | Recombinant full length Human Cripto1 with MBP tag; 596 amino acids with tag, MWt 65.8kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an epidermal growth factor-related protein that contains a cripto, FRL-1, and cryptic domain. The encoded protein is an extracellular, membrane-bound signaling protein that plays an essential role in embryonic development and tumor growth. Mutations in this gene are associated with forebrain defects. Pseudogenes of this gene are found on chromosomes 2, 3, 6, 8, 19 and X. Alternate splicing results in multiple transcript variants. |
Conjugation : | MBP |
Source : | E. coli |
Tissue specificity : | Preferentially expressed in gastric and colorectal carcinomas than in their normal counterparts. |
Form : | Lyophilised |
Storage buffer : | Preservative: NoneConstituents: PBS, pH 7.4 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Contains 1 EGF-like domain. |
Gene Name : | TDGF1 teratocarcinoma-derived growth factor 1 [ Homo sapiens ] |
Official Symbol : | TDGF1 |
Synonyms : | TDGF1; teratocarcinoma-derived growth factor 1; CR; CRIPTO; Cripto 1; |
Gene ID : | 6997 |
mRNA Refseq : | NM_001174136 |
Protein Refseq : | NP_001167607 |
Uniprot ID : | P13385 |
Chromosome Location : | 3p21.31 |
Pathway : | Developmental Biology, organism-specific biosystem; Glypican 1 network, organism-specific biosystem; Regulation of Signaling by NODAL, organism-specific biosystem; Signaling by NODAL, organism-specific biosystem; |
Function : | growth factor activity; protein binding; receptor binding; |
Products Types
◆ Recombinant Protein | ||
TDGF1-1254R | Recombinant Rat TDGF1 protein(Met1-Cys143), His-tagged | +Inquiry |
TDGF1-001H | Recombinant Human TDGF1 Protein, MBP-tagged | +Inquiry |
TDGF1-562H | Recombinant Human TDGF1 Protein, Fc-tagged | +Inquiry |
TDGF1-295H | Recombinant Human TDGF1 Protein, His-tagged(C-ter) | +Inquiry |
TDGF1-1048H | Recombinant Human TDGF1 protein(Met1-Thr172), hFc-tagged | +Inquiry |
◆ Lysates | ||
TDGF1-832RCL | Recombinant Rat TDGF1 cell lysate | +Inquiry |
TDGF1-2432HCL | Recombinant Human TDGF1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMutations in the TDGF1 gene have been linked to certain congenital disorders. Understanding these genetic associations can provide insights into the underlying mechanisms of these conditions.
TDGF1 has been found to play a role in neural development. It is involved in the specification of neural cell fate and the formation of the neural tube during embryogenesis.
Yes, efforts are underway to develop drugs that modulate TDGF1 activity. Targeting TDGF1 could potentially lead to novel therapies for conditions related to cell growth and differentiation.
TDGF1 is involved in the maintenance of pluripotency in embryonic stem cells. Understanding its role could enhance our ability to control and manipulate stem cells for therapeutic purposes.
Researchers are exploring the use of TDGF1 as a biomarker for certain cancers. Detection of elevated TDGF1 levels in patient samples may aid in early cancer diagnosis.
Customer Reviews (3)
Write a reviewthe manufacturer can assist in sourcing complementary reagents and tools, such as specific antibodies or detection systems, to complement the use of TDGF1 protein in trials.
manufacturers often have a wealth of knowledge and expertise in the field of TDGF1 protein research.
They may offer educational resources such as technical guides, protocols, and application notes, which can aid researchers in understanding the principles, techniques, and potential applications of TDGF1 protein in their studies.
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