Recombinant Human TFAP2A

• Cat.No.: TFAP2A-27355TH
• Product Overview: Recombinant fragment of Human AP2 alpha with N-terminal proprietary tag.Mol Wt 37.4 kDa inclusive of tag.

Specification

• Description: The protein encoded by this gene is a transcription factor that binds the consensus sequence 5-GCCNNNGGC-3. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.
• Protein length: 107 amino acids
• Molecular Weight: 37.400kDa inclusive of tags
• Source: Wheat germ
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: SGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGL GDLSIHSLPHAIEEVPHVEDPGINIPDQTVIKKGPVSLSK SNSNAVSAIPINKDNLFGGVVNPNEVF
• Sequence Similarities: Belongs to the AP-2 family.

Gene Information

• Gene Name: TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) [ Homo sapiens ]
• Official Symbol: TFAP2A
• Synonyms: TFAP2A; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); AP2TF, TFAP2, transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha); transcription factor AP-2-alpha; AP 2
• Gene ID: 7020
• mRNA Refseq: NM_001032280
• Protein Refseq: NP_001027451
• MIM: 107580
• Uniprot ID: P05549
• Chromosome Location: 6pter-p22.3
• Pathway: Caspase cascade in apoptosis, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem
• Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; RNA polymerase II core promoter proximal region sequence-specific D