"TFF1" Related Products


Recombinant Human TFF1, His-tagged

Cat.No.: TFF1-27975TH
Product Overview: Recombinant full length Human Estrogen Inducible Protein pS2 with an N-Terminal His-tag, 70 amino acids, Predicted MWt 7.9 kDa.
Description: Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Conjugation: HIS
Source: E. coli
Tissue specificity: Found in stomach, with highest levels in the upper gastric mucosal cells (at protein level). Detected in goblet cells of the small and large intestine and rectum, small submucosal glands in the esophagus, mucous acini of the sublingual gland, submucosal g
Form: Liquid
Purity: >95% by SDS-PAGE
Storage buffer: Preservative: NoneConstituents: 20mM Sodium chloride, 20mM Tris, pH 7.5
Storage: Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities: Contains 1 P-type (trefoil) domain.
Gene Name: TFF1 trefoil factor 1 [ Homo sapiens ]
Official Symbol: TFF1
Synonyms: TFF1; trefoil factor 1; BCEI, breast cancer, estrogen inducible sequence expressed in; D21S21; HP1.A; HPS2; pNR 2; pS2;
Gene ID: 7031
mRNA Refseq: NM_003225
Protein Refseq: NP_003216
MIM: 113710
Uniprot ID: P04155
Chromosome Location: 21q22.3
Pathway: FOXA1 transcription factor network, organism-specific biosystem;
Function: growth factor activity; protein binding;

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