Recombinant Human TNNC2

• Cat.No.: TNNC2-29819TH
• Product Overview: Recombinant full length human Troponin C; amino acids 1-160 , 18.1kDa.

Specification

• Description: Troponin (Tn), a key protein complex in the regulation of striated muscle contraction, is composed of 3 subunits. The Tn-I subunit inhibits actomyosin ATPase, the Tn-T subunit binds tropomyosin and Tn-C, while the Tn-C subunit binds calcium and overcomes the inhibitory action of the troponin complex on actin filaments. The protein encoded by this gene is the Tn-C subunit.
• Source: E. coli
• Form: Liquid
• Purity: >95% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, 1mM DTT, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MTDQQAEARS YLSEEMIAEF KAAFDMFDAD GGGDISVKEL GTVMRMLGQT PTKEELDAII EEVDEDGSGT IDFEEFLVMM VRQMKEDAKG KSEEELAECF RIFDRNADGY IDPEELAEIF RASGEHVTDE EIESLMKDGD KNNDGRIDFD EFLKMMEGVQ

Gene Information

• Gene Name: TNNC2 troponin C type 2 (fast) [ Homo sapiens ]
• Official Symbol: TNNC2
• Synonyms: TNNC2; troponin C type 2 (fast); troponin C2, fast; troponin C, skeletal muscle
• Gene ID: 7125
• mRNA Refseq: NM_003279
• Protein Refseq: NP_003270
• MIM: 191039
• Uniprot ID: P02585
• Chromosome Location: 20q12-q13.11
• Pathway: Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem
• Function: contributes_to actin binding; calcium ion binding