"TRDMT1" Related Products

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Recombinant Human TRDMT1

Cat.No.: TRDMT1-28370TH
Product Overview: Recombinant full length Human Dnmt2 with N terminal proprietary tag, 69.08kDa.
Description: This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa.
Protein length: 391 amino acids
Molecular Weight: 69.080kDa inclusive of tags
Source: Wheat germ
Tissue specificity: Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes.
Form: Liquid
Purity: Proprietary Purification
Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids: MEPLRVLELYSGVGGMHHALRESCIPAQVVAAIDVNTVAN EVYKYNFPHTQLLAKTIEGITLEEFDRLSFDMILMSPPCQ PFTRIGRQGDMTDSRTNSFLYILDILPRLQKLPKYILLEN VKGFEVSSTRDLLIQTIENCGFQYQEFLLSPTSLGIPNSR LRYFLIAKLQSEPLPFQAPGQVLMEFPKIESVHPQKYAMD VENKIQEKNVEPNISFDGSIQCSGKDAILFKLETAEEIHR KNQQDSDLSVKMLKDFLEDDTDVNQYLLPPKSLLRYALLL DIVQPTCRRSVCFTKGYGSYIEGTGSVLQTAEDVQVENIY KSLTNLSQEEQITKLLILKLRYFTPKEIANLLGFPPEFGF PEKITVKQRYRLLGNSLNVHVVAKLIKILYE
Sequence Similarities: Belongs to the C5-methyltransferase family.
Gene Name: TRDMT1 tRNA aspartic acid methyltransferase 1 [ Homo sapiens ]
Official Symbol: TRDMT1
Synonyms: TRDMT1; tRNA aspartic acid methyltransferase 1; DNA (cytosine 5 ) methyltransferase 2 , DNMT2; tRNA (cytosine(38)-C(5))-methyltransferase; RNMT1;
Gene ID: 1787
mRNA Refseq: NM_004412
Protein Refseq: NP_004403
MIM: 602478
Uniprot ID: O14717
Chromosome Location: 10p15.1
Function: DNA (cytosine-5-)-methyltransferase activity; DNA binding; RNA binding; methyltransferase activity; transferase activity;

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