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Recombinant Human TRIP13, T7 -tagged

Cat.No. : TRIP13-31615TH
Product Overview : Recombinant full length protein (Human) fused with T7 tag at N-terminus.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a protein that interacts with thyroid hormone receptors, also known as hormone-dependent transcription factors. The gene product interacts specifically with the ligand binding domain. This gene is one of several that may play a role in early-stage non-small cell lung cancer.
Conjugation : T7
Source : E. coli
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : Preservative: 0.002% Sodium AzideConstituents: 0.1% Triton X-100, 10mM Tris, pH 8.0
Storage : Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Sequence Similarities : Belongs to the AAA ATPase family.
Gene Name : TRIP13 thyroid hormone receptor interactor 13 [ Homo sapiens ]
Official Symbol : TRIP13
Synonyms : TRIP13; thyroid hormone receptor interactor 13; pachytene checkpoint protein 2 homolog; 16E1BP; thyroid receptor interacting protein 13;
Gene ID : 9319
mRNA Refseq : NM_004237
Protein Refseq : NP_004228
MIM : 604507
Uniprot ID : Q15645
Chromosome Location : 5p15
Function : ATP binding; identical protein binding; nucleoside-triphosphatase activity; nucleotide binding; protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does TRIP13 play in DNA repair mechanisms? 07/26/2022

TRIP13 plays a role in DNA repair, contributing to genomic stability and integrity.

What is the impact of altered TRIP13 activity on cancer development? 05/10/2022

Altered TRIP13 activity is linked with cancer progression due to its role in cell cycle regulation.

What is the primary role of TRIP13 in cell cycle regulation? 02/25/2022

TRIP13 is crucial for the regulation of the cell cycle, particularly in the transition between different phases.

What potential therapeutic applications arise from targeting TRIP13 in cancer therapy? 12/27/2020

Targeting TRIP13 could provide a novel approach in cancer treatment, focusing on its role in cell cycle regulation.

How do genetic variations in TRIP13 affect cellular division and stability? 01/29/2018

Mutations in TRIP13 can lead to errors in cell division and increased genomic instability.

How does TRIP13 contribute to chromosome segregation during mitosis? 10/08/2017

It assists in proper chromosome segregation, ensuring accurate cell division during mitosis.

How does TRIP13 interact with other proteins in cell cycle and DNA repair pathways? 03/14/2017

TRIP13 works with other proteins to coordinate cell cycle progression and DNA repair processes.

Customer Reviews (3)

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Reviews
10/27/2018

    Dependable for data accuracy. Aids research productivity.

    08/01/2017

      Precision in analysis. Supports our research consistently.

      07/17/2017

        Efficient and timely service. Critical for research progress.

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