Recombinant Human UGP2

• Cat.No.: UGP2-31662TH
• Product Overview: Recombinant full length human UGP2 produced in Saccharomyces cerevisiae. Protein is tagged with 26 kDa proprietary tag.

Specification

• Description: The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MSRFVQDLSK AMSQDGASQF QEVIRQELEL SVKKELEKIL TTASSHEFEH TKKDLDGFRK LFHRFLQEKG PSVDWGKIQR PPEDSIQPYE KIKARGLPDN ISSVLNKLVV VKLNGGLGTS MGCKGPKSLI GVRNENTFLD LTVQQIEHLN KTYNTDVPLV LMNSFNTDED TKKILQKYNH CRVKIYTFNQ SRYPRINKES LRPVAKDVSY SGENTEAWYP PGHGDIYASF YNSGLLDTFI GEGKEYIFVS NIDNLGATVD LYILNHLINP PNGKRCEFVM EVTNKTRADV KGGTLTQYEG KLRLVEIAQV PKAHVDEFKS VSKFKIFNTN NLWISLAAVK RLQEQNAIDM EIIVNAKTLD GGLNVIQLET AVGAAIKSFE NSLGINVPRS RFLPVKTTSD LLLVMSNLYS LNAGSLTMSE KREFPTVPLV KLGSSFTKVQ DYLRRFESIP DMLELDHLTV SGDVTFGKNV SLKGTVIIIA NHGDRIDIPP GAVLENKIVS GNLRILDH

Gene Information

• Gene Name: UGP2 UDP-glucose pyrophosphorylase 2 [ Homo sapiens ]
• Official Symbol: UGP2
• Synonyms: UGP2; UDP-glucose pyrophosphorylase 2; UTP--glucose-1-phosphate uridylyltransferase
• Gene ID: 7360
• mRNA Refseq: NM_001001521
• Protein Refseq: NP_001001521
• MIM: 191760
• Uniprot ID: Q16851
• Chromosome Location: 2p14-p13
• Pathway: Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; Ascorbate biosynthesis, animals, glucose-1P => ascorbate, organism-specific biosystem; Ascorbate biosynthesis, animals, glucose-1P =>
• Function: UTP:glucose-1-phosphate uridylyltransferase activity; UTP:glucose-1-phosphate uridylyltransferase activity; glucose binding; metal ion binding; nucleotidyltransferase activity