"TGFB3" Related Products

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Recombinant Human Transforming Growth Factor, Beta 3

Cat. No.: TGFB3-349H
Description: Transforming growth factor-beta 3 (TGF-beta 3) is a member of the TGF beta family of growth factors. It is involved in oxygen-dependent differentiation processes during placental development and pregnancy disorders. It also play an important role in wound repair and scarring.
Source: Sf21 Insect Cells.
Molecular Weight: The predicted molecular weight of Recombinant Human TGF-β3 is Mr 25 kDa.
State Of Matter: Lyophilized.
Purity: >97% by SDS Page and analyzed by silver stain.
Endotoxin: <1.0 EU/µg as determined by the LAL method.
Formulation: This recombinant protein was lyophilized from a 0.2 μm filtered solution in 40% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Biological Activity: The biological activity of Human TGF-β3 was determined by its ability to inhibit the IL-4-dependent proliferation of mouse HT-2 cells. The expected ED50 for this effect is typically 0.03 - 0.08 ng/ml.
Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Gene Name: TGFB3 transforming growth factor, beta 3 [ Homo sapiens ]
Synonyms: Transforming Growth Factor-beta3; TGFB3; ARVD; FLJ16571; TGF-beta3; transforming growth factor, beta 3
Gene ID: 7043
mRNA Refseq: NM_003239
Protein Refseq: NP_003230
MIM: 190230
UniProt ID: P10600
Chromosome Location: 14q24
Pathway: Cell cycle; Chronic myeloid leukemia; Colorectal cancer; Cytokine-cytokine receptor interaction; Hypertrophic cardiomyopathy (HCM); MAPK signaling pathway; Pancreatic cancer;Pathways in cancer; Renal cell carcinoma; TGF-beta signaling pathway
Function: Growth factor activity; Identical protein binding; Protein heterodimerization activity; Transforming growth factor beta binding; Type I transforming growth factor beta receptor binding; Type II transforming growth factor beta receptor binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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