"PTGES3" Related Products

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Recombinant Human Prostaglandin E Synthase 3 (Cytosolic)

Cat. No. : PTGES3-478H
Product Overview : Recombinant human PTGES3 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 18.6 kDa (160aa).
Description : Prostaglandin E synthase 3 (PTGES3), also known as P23 or TEBP (Telomerase binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. This protein is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
Source : E.coli.
Amino Acid Sequence : MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE
Form : Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol.
Purity : > 95% by SDS – PAGE.
Concentration : 0.5 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
Gene Name : PTGES3 prostaglandin E synthase 3 (cytosolic) [ Homo sapiens ]
Synonyms : PTGES3 prostaglandin E synthase 3 (cytosolic); P23; TEBP; cPGES; prostaglandin-E synthase 3; Hsp90 co-chaperone; telomerase-binding protein p23; progesterone receptor complex p23; cytosolic prostaglandin E synthase; unactive progesterone receptor, 23 Kd; EC 5.3.99.3; Cytosolic prostaglandin E2 synthase
Gene ID : 10728
mRNA Refseq : NM_006601
Protein Refseq : NP_006592
MIM : 607061
UniProt ID : Q15185
Chromosome Location : 12q13.3; 12
Function : isomerase activity; prostaglandin-E synthase activity; telomerase activity; unfolded protein binding

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