Recombinant Human Prostaglandin E Synthase 3 (Cytosolic)

• Cat.No.: PTGES3-478H
• Product Overview: Recombinant human PTGES3 protein was expressed inE.coliand purified by using conventional chromatography techniques. MW = 18.6 kDa (160aa).

Specification

• Cat. No.: PTGES3-478H
• Description: Prostaglandin E synthase 3 (PTGES3), also known as P23 or TEBP (Telomerase binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. This protein is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
• Source: E.coli.
• Amino Acid Sequence: MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT 10% glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PTGES3 prostaglandin E synthase 3 (cytosolic) [ Homo sapiens ]
• Synonyms: PTGES3 prostaglandin E synthase 3 (cytosolic); P23; TEBP; cPGES; prostaglandin-E synthase 3; Hsp90 co-chaperone; telomerase-binding protein p23; progesterone receptor complex p23; cytosolic prostaglandin E synthase; unactive progesterone receptor, 23 Kd; EC 5.3.99.3; Cytosolic prostaglandin E2 synthase
• Gene ID: 10728
• mRNA Refseq: NM_006601
• Protein Refseq: NP_006592
• MIM: 607061
• UniProt ID: Q15185
• Chromosome Location: 12q13.3; 12
• Function: isomerase activity; prostaglandin-E synthase activity; telomerase activity; unfolded protein binding