"PRPS1" Related Products

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Recombinant Human PRPS1, His-tagged

Cat. No. : PRPS1-494H
Product Overview : Recombinant human PRPS1 protein fused to His-tag at N-terminus was expressed inE.coliand purified by using conventional chromatography techniques. MW = 36.9 kDa (338aa).
Description : PRPS1, also known as ribose-phosphate pyrophosphokinase 1, is ubiquitously expressed in human tissues. This enzyme catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis.
Source : E.coli.
Form : Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 0.1 M NaCl, and 20% glycerol.
Purity : > 90% by SDS – PAGE.
Concentration : 1 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MGSSHHHHHH SSGLVPRGSH MPNIKIFSGS SHQDLSQKIA DRLGLELGKV VTKKFSNQET CVEIGESVRG EDVYIVQSGC GEINDNLMELLIMINACKIA SASRVTAVIP CFPYARQDKK DKSRAPISAK LVANMLSVAG ADHIITMDLH ASQIQGFFDI PVDNLYAEPA VLKWIRENIS EWRNCTIVSP DAGGAKRVTS IADRLNVDFA LIHKERKKAN EVDRMVLVGD VKDRVAILVD DMADTCGTIC HAADKLLSAG ATRVYAILTHGIFSGPAISR INNACFEAVV VTNTIPQEDK MKHCSKIQVI DISMILAEAI RRTHNGESVS YLFSHVPL.
Storage : can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : PRPS1 phosphoribosyl pyrophosphate synthetase 1 [ Homo sapiens ]
Synonyms : phosphoribosyl pyrophosphate synthetase 1; ARTS; DFN2; PRSI; CMTX5; DFNX1; PPRibP; KIAA0967; PRPS1; ribose-phosphate pyrophosphokinase 1; PRS-I; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1);PRS-I; Phosphoribosyl pyrophosphate synthetase I; EC 2.7.6.1
Gene ID : 5631
mRNA Refseq : NM_002764
Protein Refseq : NP_002755
MIM : 311850
UniProt ID : P60891
Chromosome Location : Xq21.32-q24
Pathway : Metabolic pathways; Pentose phosphate pathway; Purine metabolism; Metabolism of carbohydrates
Function : ADP binding; AMP binding; ATP binding; GDP binding; kinase activity; magnesium ion binding; nucleotide binding; protein homodimerization activity; ribose phosphate diphosphokinase activity; sugar binding; transferase activity

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