"IL1B" Related Products

Expand
Expand

Recombinant Equine Interleukin 1, Beta

Cat. No.: IL1B-251E
Product Overview: Recombinant Equine IL-1 beta was expressed inYeast.MW= 17.3 kDa (153 aa).
Description: IL-1 beta is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1 alpha and IL-1 beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1 beta is a secreted cytokine, IL-1 alpha is predominantly a cell-associated cytokine.
Source: Yeast.
Formulation/ Reconstitution: Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein.
Purification: Ion-exchange chromatography.
Purity: >95% as visualized by SDS-PAGE analysis.
Amino Acid Sequence: AAVHSVNCRL RDIYHKSLVL SGACELQAVH LNGENTNQQV VFCMSFVQGE EETDKIPVAL GLKEKNLYLS CGMKDGKPTL QLETVDPNTY PKRKMEKRFV FNKMEIKGNV EFESAMYPNW YISTSQAEKK PVFLGNTRGG RDITDFIMEI TSA.
Bioactivity: The biological activity of recombinant equine IL-1 beta was measured in a cell proliferation assay using the mouse D10S cell line. The ED50 for this effect is typically 9.0 - 14.0 pg/mL.
Stability And Storage: Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles.
Gene Name: IL1B interleukin 1, beta [ Equus caballus ]
Synonyms: interleukin 1, beta; IL1B; IL-1B;IL-1 beta; interleukin-1 beta
Gene ID: 100034237
mRNA Refseq: NM_001082526.1
Protein Refseq: NP_001075995.1
UniProt ID: Q28386
Chromosome Location: Un
Pathway: Alzheimer"s disease; Apoptosis; Cytokine-cytokine receptor interaction; Cytosolic DNA-sensing pathway; Graft-versus-host disease; Hematopoietic cell lineage; MAPK signaling pathway; NOD-like receptor signaling pathway; Prion diseases; Toll-like receptor signaling pathway; Type I diabetes mellitus

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.