Recombinant Human PTGS2

• Cat.No.: PTGS2-523H
• Product Overview: Recombinant Human PTGS2 wasexpressed inSf21 cells.

Specification

• Cat. No.: PTGS2-523H
• Description: Prostaglandin-endoperoxide synthase 2, also known as cyclooxygenase-2 or simply COX-2, is an enzyme which in humans is encoded by the PTGS2 gene.
• Source: Sf21 cells.
• Purity: 70%.
• Unit Definition: 1 unit equals 1 nanogram of purified protein.
• Buffer: 80 mM Tris -HCl, pH 8.0, containing 0.1% Tween 20 and 300 M DDC.
• Storage: -80°C, AVOID repeated freeze & thawing.

Gene Information

• Gene Name: PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) [ Homo sapiens ]
• Synonyms: PTGS2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase); PGH synthase 2; PHS II; cyclooxygenase 2b; cyclooxygenase-2; prostaglandin G/H synthase 2; prostaglandin G/H synthase and cyclooxygenase; prostaglandin H2 synthase 2; COX2; COX-2; PHS-2; PGG/HS; PGHS-2; hCox-2; GRIPGHS; PTGS2; EC 1.14.99.1
• Gene ID: 5743
• mRNA Refseq: NM_000963
• Protein Refseq: NP_000954
• MIM: 600262
• UniProt ID: P35354
• Chromosome Location: 1q25.2-q25
• Pathway: Arachidonic acid metabolism; Pathways in cancer; Small cell lung cancer; VEGF signaling pathway; Biological oxidations
• Function: heme binding; lipid binding; oxidoreductase activity; metal ion binding; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; peroxidase activity; peroxidase activity; prostaglandin-endoperoxide synthase activity; protein binding