Recombinant Mouse Fibroblast Growth Factor 21, FLAG-tagged

• Cat.No.: Fgf21-414M
• Product Overview: Recombinant mouse fibroblast growth factor 21 (FGF-21) (aa 1-210) produced inHEK 293 cellsis fused at the C-terminus to a FLAG-tag.

Specification

• Cat. No.: Fgf21-414M
• Description: FGF-21 is preferentially expressed in liver, but an exact knowledge of FGF-21 bioactivity and its mode of action have been lacking to date. FGF-21 is a potent activator of glucose uptake on adipocytes, protects animals from diet-induced obesity when overexpressed in transgenic mice, and lowers blood glucose and triglyceride levels when therapeutically administered to diabetic rodents.
• Source/Host: HEK 293 cells.
• Purity: ≥90% (SDS-PAGE).
• Formulation: Liquid. 0.2μm-filtered solution in PBS.
• Concentration: 250μg/ml.
• Endotoxin Content: <1EU/µg protein (LAL-test).
• Long Term Storage: -20°C.
• Use/Stability: Working aliquots are stable for up to 3 months when stored at -20°C.
• Handling: Avoid freeze/thaw cycles.After opening, prepare aliquots and store at -20°C.

Gene Information

• Gene Name: Fgf21 fibroblast growth factor 21 [ Mus musculus ]
• Synonyms: Fgf21; fibroblast growth factor 21;FGF-21
• Gene ID: 56636
• mRNA Refseq: NM_020013
• Protein Refseq: NP_064397
• UniProt ID: Q9JJN1
• Chromosome Location: 7 B2
• Pathway: MAPK signaling pathway; Melanoma; Pathways in cancer; Regulation of actin cytoskeleton
• Function: growth factor activity