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Recombinant Mouse Indoleamine 2,3-dioxygenase 1, His-tagged

Cat.No. : Ido1-2126M
Product Overview : Recombinant Mouse Ido1 was produced inE. coli.Mature mouse IDO (indoleamine 2,3-dioxygenase) (aa 1-407) is fused at the C-terminus to a His-tag.
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Cat. No. : Ido1-2126M
Description : Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO EC 1.13.11.52) is an immunomodulatory enzyme produced by some alternatively activated macrophages and other immunoregulatory cells (also used as an immune subversion strategy by many tumors). IDO is the first and rate-limiting enzyme of tryptophan catabolism through kynurenine pathway, thus causing depletion of tryptophan which can cause halted growth of microbes as well as T cells.
Source : E. coli.
Purity : ≥90% (SDS-PAGE).
Formulation : Liquid. 0.2µm-filtered solution in 50mM TRIS, pH 7.4, containing 1mM EDTA.
Concentration : 1mg/ml.
Endotoxin Content : <1EU/µg protein (LAL-test).
Specific Activity : >100'000U/mg protein with L-tryptophan as substrate. One unit is defined as the amount of enzyme that produces 1nmol of kynurenine per hour.
Storage : Working aliquots are stable for up to 3 months when stored at -20°C.
Gene Name : Ido1 indoleamine 2,3-dioxygenase 1 [ Mus musculus ]
Synonyms : Ido1; indoleamine 2,3-dioxygenase 1; Ido; Indo; IDO-1; OTTMUSP00000022551; indole 2,3-dioxygenase; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase; EC 1.13.11.52
Gene ID : 15930
mRNA Refseq : NM_008324
Protein Refseq : NP_032350
UniProt ID : P28776
Chromosome Location : 8 A2
Pathway : Metabolic pathways; Tryptophan metabolism
Function : amino acid binding; heme binding; indoleamine 2,3-dioxygenase activity; metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; oxygen binding; tryptophan 2,3-dioxygenase activity

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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08/12/2022

    The product was kept in perfect condition and delivered on time so that I got the perfect product in the shortest time possible.

    05/14/2022

      Customer service contacted me in a timely manner and helped me solve a lot of problems that arose in my experiments.

      03/12/2022

        The purchased proteins helped me to get satisfactory experimental results.

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