"CDK2AP1" Related Products

Expand

Recombinant Human CDK2AP1, His-tagged

Cat. No. : CDK2AP1-1936H
Product Overview : Recombinant CDK2AP1 protein fused to his-tag was expressed inE.coliand purified by using conventional chromatography techniques. 16.6kDa (152aa).
Description : CDK2AP1 is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. Also, interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.
Source : E.coli.
Purity : > 95% by SDS – PAGE.
Physical Appearance : Liquid.
Formulation : 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 2mM DTT.
Concentration : 0.25 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMSY KPNLAA H MPA AALNAAGSVH SPSTSMATSS QYRQLLSDYG PPSLGYT QGTGNS QV P Q S KY AELLAIIEEL GKEIRPTYAG SKSAMERLKR GIIHARGLVR ECLAET ERNA R S.
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : CDK2AP1 cyclin-dependent kinase 2 associated protein 1 [ Homo sapiens ]
Synonyms : CDK2AP1; cyclin-dependent kinase 2 associated protein 1; DOC1; ST19; DORC1; doc-1; p12DOC-1; CDK2-associated protein 1; Deleted in oral cancer-1; deleted in oral cancer 1; putative oral cancer suppressor; cyclin-dependent kinase 2-associated protein 1; CDKAP1
Gene ID : 8099
mRNA Refseq : NM_004642
Protein Refseq : NP_004633
MIM : 602198
UniProt ID : O14519
Chromosome Location : 12q24.31
Function : DNA binding; protein binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.