Recombinant Human NME2

• Cat.No.: NME2-1946H
• Product Overview: Recombinant human NME2 protein was expressed inE.coliand purified by using conventional chromatography techniques. 17.2 kDa (152aa).

Specification

• Cat. No.: NME2-1946H
• Description: NME2, also known as NM23B, is a heterodimeric protein functioning as a nucleoside diphosphate (NDP) kinase. NME1 and NME2 comprise the 152 amino acid A and B polypeptide chains of the NM23 enzyme, respectively. NME2 is identical to the beta subunit of human erythrocyte NDP kinase. NDP kinases are involved in the synthesis of nucleoside triphosphates, and NM23 may act in the regulation of signal transduction by complexing with G proteins, causing activation/inactivation of developmental pathways.
• Source: E.coli.
• Purity: > 95% by SDS - PAGE.
• Physical Appearance: Liquid.
• Formulation: In 20 mM Tris-HCl buffer (pH8.0) containing 1mM DTT, 10% glycerol.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MANLERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVAMKF LRASEEHLKQ HYI DLK DRPF FPGLVKYMNS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTI RGDFCI QVGRNIIHGS DSVKSAEKEI SLWFKPEELV DYKSCAHDWV YE.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Metabolic pathways; Purine metabolism; Pyrimidine metabolism; Metabolism of nucleotides

Gene Information

• Gene Name: NME2 non-metastatic cells 2, protein (NM23B) expressed in [ Homo sapiens ]
• Synonyms: NME2; non-metastatic cells 2, protein (NM23B) expressed in; puf; NDPKB; NM23B; NDPK-B; NM23-H2; MGC111212; nucleoside diphosphate kinase B; NDK B; NDP kinase B; c-myc transcription factor; C-myc purine-binding transcription factor PUF; non-metastatic cells 2, protein (NM23) expressed in; OTTHUMP00000174775; OTTHUMP00000174728; OTTHUMP00000174776; OTTHUMP00000174774; EC 2.7.4.6
• Gene ID: 4831
• mRNA Refseq: NM_001018137
• Protein Refseq: NP_001018147
• MIM: 156491
• UniProt ID: P22392
• Chromosome Location: 17q21.3