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Recombinant Human IL22RA2, His tagged

Cat.No. : IL22RA2-2258H
Product Overview : Recombinant Human IL22RA2 (NP_851826.1) (Met 1-Pro 231), fused with a polyhistidine tag at the C-terminus, was produced in Human Cell.
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Source : Human Cells
Species : Human
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4
Molecular Mass : The secreted recombinant human IL22RA2 comprises 221 amino acids with a predicted molecular mass of 26.1 kDa. As a result of glycosylation, rh IL22RA2 migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : IL22RA2 interleukin 22 receptor, alpha 2 [ Homo sapiens ]
Official Symbol : IL22RA2
Gene ID : 116379
mRNA Refseq : NM_052962
Protein Refseq : NP_443194
MIM : 606648
UniProt ID : Q969J5

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (10)

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How does IL22RA2 interact with IL22 at the molecular level? 09/30/2022

IL22RA2 binds to IL22, acting as a decoy receptor.

Can IL22RA2 be targeted for autoimmune disease therapy? 08/23/2022

IL22RA2 is a potential therapeutic target for autoimmune diseases.

What cellular pathways are influenced by IL22RA2? 07/07/2022

IL22RA2 influences the JAK-STAT and NF-κB pathways.

Does IL22RA2 expression correlate with disease severity? 03/16/2022

IL22RA2 expression correlates with disease severity in psoriasis.

What are the kinetics of IL22RA2 and IL22 binding? 01/18/2022

IL22RA2 has high binding kinetics with IL22.

Is IL22RA2 involved in epithelial barrier function? 01/09/2022

IL22RA2 is involved in maintaining epithelial barrier integrity.

How does IL22RA2 expression change during infection? 04/14/2020

IL22RA2 expression is upregulated during bacterial infection.

What is the turnover rate of IL22RA2 in cells? 12/31/2018

The turnover rate of IL22RA2 in cells is approximately 24 hours.

Does IL22RA2 have any alternative splicing variants? 06/13/2018

IL22RA2 has multiple alternative splicing variants.

What post-translational modifications occur on IL22RA2? 03/29/2017

IL22RA2 undergoes phosphorylation.

Customer Reviews (3)

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Reviews
08/26/2020

    Potent in Th17 activation.

    09/26/2017

      High specificity.

      06/21/2016

        Good for cytokine assays.

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