"RANBP2" Related Products

Recombinant Human RAN Binding Protein 2, GST-tagged

Cat. No.: RANBP2-2386H
Product Overview: Recombinant Human RAN Binding Protein 2(aa 2553-2838) with a GST tag is Expressed inE. coli.MW= 59 kDa.
Description: RanBP2 directly interacts with the E2 enzyme Ubc9 and strongly enhances SUMO-1 transfer from Ubc9 to the SUMO-1 target Sp100, Mdm2, a GTPase activating protein with essential functions in nucleocytoplasmic transport and mitosis.
Source: E. coli.
Purity: Purified using GST-based chromatography.
Biological Activity: The enzyme facilitates in vitro SUMOylation using SUMO-1 (BML-UW9195), SUMO E1 (BML-UW9330), and SUMO E2 UbcH9 (BML-UW9320).
Storage: -80°C.
Gene Name: RANBP2 RAN binding protein 2 [ Homo sapiens ]
Synonyms: RANBP2; RAN binding protein 2; ANE1; TRP1; TRP2; NUP358; 358 kDa nucleoporin; E3 SUMO-protein ligase RanBP2; P270; nuclear pore complex protein Nup358; nucleoporin 358; nucleoporin Nup358; ran-binding protein 2; transformation-related protein 2
Gene ID: 5903
mRNA Refseq: NM_006267
Protein Refseq: NP_006258
MIM: 601181
UniProt ID: P49792
Chromosome Location: 2q12.3
Pathway: Cell Cycle, Mitotic; HIV Infection; Metabolism of carbohydrates; Transmembrane transport of small molecules
Function: Ran GTPase binding; isomerase activity; metal ion binding; peptidyl-prolyl cis-trans isomerase activity; protein binding; zinc ion binding

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