|Cat. No. :
|Product Overview :
||Recombinant signal peptide and extracellular domain of human SIGIRR (aa 1-118) produced inHEK 293 cellsare fused at the C-terminus to the Fc portion of human IgG.
||Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family. It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling. It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.
||HEK 293 cells.
|Endotoxin Content :
||<0.1EU/µg protein (LAL-test).
||Liquid. 0.2µm-filtered solution in PBS.
|Long Term Storage :
||Working aliquots are stable for up to 3 months when stored at -20°C.
||After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles.