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Recombinant Human SERPINE1, Active Form

Cat. No. : SERPINE1-2458H
Product Overview : Recombinant glycosylated wild type human PAI-1 was produced ininsect cellswith molecular weight of ~46,000 Da. Active form.
Description : Plasminogen activator inhibitor-1(PAI-1), a member of the serine protease inhibitor (serpin) super family. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, the activators of plasminogen and hence fibrinolysis. PAI-1 is mainly produced by the endothelium but is also secreted by other tissue types, such as adipose tissue.
Source : Insect cell culture.
Concentration : 2.5 mg/ml.
Buffer : 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6.
Form : Frozen liquid.
Minimum Shelf Life : 3 years from delivery.
Storage : -70℃.
Gene Name : SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 [ Homo sapiens ]
Synonyms : SERPINE 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; PAIE; Clade E; PLANH1; SERPINE1; PAI; PAI-1; PAI1; plasminogen activator inhibitor-1; plasminogen activator inhibitor, type I; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Endothelial plasminogen activator inhibitor
Gene ID : 5054
mRNA Refseq : NM_000602
Protein Refseq : NP_000593
MIM : 173360
UniProt ID : P05121
Chromosome Location : 7q21.3-q22
Pathway : Complement and coagulation cascades; Hemostasis
Function : peptidase inhibitor activity; protease binding; protein binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity;serine-type endopeptidase inhibitor activity

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