Recombinant Human SERPINE1, Active Form

• Cat.No.: SERPINE1-2458H
• Product Overview: Recombinant glycosylated wild type human PAI-1 was produced ininsect cellswith molecular weight of ~46,000 Da. Active form.

Specification

• Cat. No.: SERPINE1-2458H
• Description: Plasminogen activator inhibitor-1(PAI-1), a member of the serine protease inhibitor (serpin) super family. PAI-1 is the principal inhibitor of tissue plasminogen activator and urokinase, the activators of plasminogen and hence fibrinolysis. PAI-1 is mainly produced by the endothelium but is also secreted by other tissue types, such as adipose tissue.
• Source: Insect cell culture.
• Concentration: 2.5 mg/ml.
• Buffer: 0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6.
• Form: Frozen liquid.
• Minimum Shelf Life: 3 years from delivery.
• Storage: -70℃.

Gene Information

• Gene Name: SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 [ Homo sapiens ]
• Synonyms: SERPINE 1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Plasminogen activator inhibitor 1; Endothelial plasminogen activator inhibitor; PAIE; Clade E; PLANH1; SERPINE1; PAI; PAI-1; PAI1; plasminogen activator inhibitor-1; plasminogen activator inhibitor, type I; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Endothelial plasminogen activator inhibitor
• Gene ID: 5054
• mRNA Refseq: NM_000602
• Protein Refseq: NP_000593
• MIM: 173360
• UniProt ID: P05121
• Chromosome Location: 7q21.3-q22
• Pathway: Complement and coagulation cascades; Hemostasis
• Function: peptidase inhibitor activity; protease binding; protein binding; serine-type endopeptidase activity; serine-type endopeptidase inhibitor activity;serine-type endopeptidase inhibitor activity