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Recombinant Human Casein Kinase 1, Delta, GST-tagged

Cat. No.: CSNK1D-678H
Product Overview: Recombinant human full length Casein Kinase 1 delta with GST tag was expressed ininsect cells.MW = 88.7 kDa.
Description: Casein kinase I isoform delta is an enzyme that in humans is encoded by the CSNK1D gene. This gene is a member of the casein kinase I (CKI) gene family whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is highly similar to the mouse and rat CK1 delta homologs. Two transcript variants encoding different isoforms have been found for this gene.
Source: Insect cells.
Formulation: Liquid in 50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2mM DTT + 50% glycerol.
Specific Activity: 282 nmole of phosphate transferred to dephosphorylated casein substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 2 μg/ml.
Storage & Stability: Stable for 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
Gene Name: CSNK1D casein kinase 1, delta [ Homo sapiens ]
Synonyms:
casein kinase 1, delta; HCKID; CSNK1D; casein kinase I isoform delta; CKId; CKI-delta; EC 2.7.11.1
Gene ID: 1453
mRNA Refseq: NM_001893
Protein Refseq: NP_001884
MIM: 600864
UniProt ID: P48730
Chromosome Location: 17q25
Pathway: Circadian rhythm – mammal; Gap junction; Hedgehog signaling pathway; Cell Cycle, Mitotic
Function: ATP binding; nucleotide binding; protein binding; protein kinase activity; protein serine/threonine kinase activity; transferase activity

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