Recombinant Mouse Rarres2

• Cat.No.: Rarres2-2627M
• Product Overview: Recombinant Mouse Retinoic Acid Receptor Responder (Tazarotene Induced) 2 is expressed inE. coli.

Specification

• Cat. No.: Rarres2-2627M
• Description: Chemerin is a potent chemoattractant, identified as the ligand of CMKLR (also known as Chem23R, DEZ), a receptor expressed by plasmacytoid DCs, and some macrophage and NK cell subsets. Pro-chemerin circulates in the blood and is biologically inactive, until processed by a variety of serine proteases at sites of tissue damage to remove six C-terminal amino acid residues. The cleaved, mature form of chemerin is biologically active and recruits CMKLR1-positive cells to sites of tissue damage. Chemerin is a member of the cystatin superfamily and contains three intrachain disulfide bonds.
• Source: E. coli.
• Purity: >98% pure as demonstrated by SDS-gel electrophoresis and reverse phase HPLC.
• Molecular Weight: 16 kDa.
• Endotoxin Level: Less than 0.01 ng/ug cytokine, as determined by the LAL assay.
• Biological Activity: Measured in a bioassay of chemerin-induced migration of CHO cells transfected with the mouse chemerin receptor, CMKLR. Maximal chemotactic activity of chemerin in this assay is typically observed at 50-100 ng/ml.
• Formulation: Sterile liquid; phosphate buffered saline, pH 7.2,150 mM NaCl, with 0.5% BSA, 0.22 μM filtered.
• Storage: Store at less than or equal to -70°C.

Gene Information

• Gene Name: Rarres2 retinoic acid receptor responder (tazarotene induced) 2 [ Mus musculus ]
• Synonyms:
  Rarres2; retinoic acid receptor responder (tazarotene induced) 2; chemerin; retinoic acid receptor responder protein 2; 0610007L05Rik; AI303516
• Gene ID: 71660
• mRNA Refseq: NM_027852
• Protein Refseq: NP_082128
• UniProt ID: Q9DD06
• Chromosome Location: 6 B2.3; 6