"RAPGEF4" Related Products

Recombinant Human Rap Guanine Nucleotide Exchange Factor (GEF) 4

Cat. No.: RAPGEF4-2637H
Product Overview: Recombinant human Rap Guanine Nucleotide Exchange Factor (GEF) 4 is expressed inE. coli.
Description: Rap guanine nucleotide exchange factor (GEF) 4 (RAPGEF4), also known as exchange protein directly activated by cAMP 2 (EPAC2), is a protein which in humans is encoded by the RAPGEF4 gene.
Source: E.coli.
Form: Liquid.
Formulation: In 150 mM NaCl, 10 mM Tris, 0.1% NP-40, pH 8.3.
Biological Activity: EC50 of cAMP binding: ≤1.5 μM.
Storage: +2°C to +8°C. Ship: Dry Ice Only.
Gene Name: RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 [ Homo sapiens ]
Synonyms:
RAPGEF4; Rap guanine nucleotide exchange factor (GEF) 4; EPAC 2; OTTHUMP00000205058; RAP guanine-nucleotide-exchange factor (GEF) 4; cAMP-regulated guanine nucleotide exchange factor II; exchange factor directly activated by cAMP 2; exchange protein directly activated by cAMP 2; putative protein product of Nbla00496; rap guanine nucleotide exchange factor 4; CGEF2; EPAC2; Nbla00496; CAMP-GEFII
Gene ID: 11069
mRNA Refseq: NM_001100397
Protein Refseq: NP_001093867
MIM: 606058
UniProt ID: Q8WZA2
Chromosome Location: 2q31-q32
Pathway: Leukocyte transendothelial migration; Diabetes pathways; Integration of energy metabolism; Integrin cell surface interactions
Function: Ras GTPase binding; Ras guanyl-nucleotide exchange factor activity; cAMP binding; cAMP-dependent protein kinase regulator activity; guanyl-nucleotide exchange factor activity; nucleotide binding; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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