Recombinant Human FIS1, His-tagged

• Cat.No.: FIS1-2477H
• Product Overview: Recombinant human TTC11, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 16.3 kDa(142aa).

Specification

• Cat. No.: FIS1-2477H
• Description: TTC11 is a component of a mitochondrial complex that promotes mitochondrial fission. This protein can induce cytochrome C release from the mitochondrion to the cytosol, ultimately leading to apoptosis. It is also involved in peroxisomal growth and division. The C terminus is required for mitochondrial localisation, while the N teminus is necessary for mitochondrial fission.
• Source: E.coli.
• Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 10% Glycerol.
• Purity: > 95% by SDS – PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MEAVLNELVS VEDLLKFEKK FQSEKAAGSV SKSTQFEYAW CLVRSKYNDD IRKGIVLLEE LLPKGSKEEQ RDYVFYLAVG NYRLKEYEKA LKYVRGLLQT EPQNNQAKEL ERLIDKAMKK DG.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) [ Homo sapiens ]
• Synonyms: fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); TTC11; CGI-135; FIS1; mitochondrial fission 1 protein; hFis1; FIS1 homolog; H_NH0132A01.6; TPR repeat protein 11; tetratricopeptide repeat domain 11; tetratricopeptide repeat protein 11;fission 1 (mitochondrial outer membrane) homolog (yeast); Fis1; Fis1 homolog; Tetratricopeptide repeat protein 11
• Gene ID: 51024
• mRNA Refseq: NM_016068
• Protein Refseq: NP_057152
• MIM: 609003
• UniProt ID: Q9Y3D6
• Chromosome Location: 7q22.1
• Function: protein binding