"RFC5" Related Products


Recombinant Human RFC5, T7-tagged

Cat. No.: RFC5-2981H
Product Overview: Recombinant Human RFC5 (1-340 aa) is expressed inE.Coliwith a T7 tag at N-terminus.
Description: The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits.
Source: E.Coli.
MW: 38497 Da.
Purity: 95%.
Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3.
Application: MS. SDS.
Gene Name: RFC5 replication factor C (activator 1) 5, 36.5kDa [ Homo sapiens ]
Synonyms: RFC5; replication factor C (activator 1) 5, 36.5kDa; A1 36 kDa subunit; OTTHUMP00000209892; RF-C 36 kDa subunit; RFC, 36.5 kD subunit; activator 1 36 kDa subunit; activator 1 subunit 5; replication factor C 36 kDa subunit; replication factor C subunit 5; MGC1155; RFC36
Gene ID: 5985
mRNA Refseq: NM_001130112
Protein Refseq: NP_001123584
MIM: 600407
UniProt ID: P40937
Chromosome Location: 12q24.23
Pathway: DNA replication; Mismatch repair; Nucleotide excision repair; Cell Cycle, Mitotic; Chromosome Maintenance; DNA Replication
Function: ATP binding; DNA clamp loader activity; nucleoside-triphosphatase activity; protein binding

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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