Recombinant Human Pyrroline-5-carboxylate Reductase 1, His-tagged
Cat.No. : | PYCR1-935H |
Product Overview : | Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 35.5 kDa(339aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | PYCR1-935H |
Description : | PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B). |
Source : | E.coli. |
Form : | Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol. |
Purity : | > 90% by SDS - PAGE. |
Concentration : | 0.5 mg/ml (determined by Bradford assay). |
Sequences Of Amino Acids : | MGSSHHHHHH SSGLVPRGSH MSVGFIGAGQ LAFALAKGFT AAGVLAAHKI MAS SPDMDLA TVSALRKMGV KLTPHNKETV QHSDVLFLAVKPHIIPFILD EIGADIEDRH IVVSC AAGVT ISSIEKKLSA FRPAPRVIRC MTNTPVVVRE GATVYATGTH AQV EDGRLME QLLSSVGFCTEVEEDLIDAV TGLSGSGPAY AFTALDALAD GGVK MGLPRR LAVRLGAQAL LGAAKMLLHS EQHPGQLKDN VSSPGGATIH ALHVL ESG GFRSLLINAVEA SCIRTRELQS MADQEQVSPA AIKKTILDKV KLDSPAGTAL SPS GHTKLLP RSLAPAGKD. |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Pathways : | Arginine and proline metabolism; Metabolic pathways; Metabolism of amino acids and derivatives |
Gene Name : | PYCR1 pyrroline-5-carboxylate reductase 1 [ Homo sapiens ] |
Synonyms : | pyrroline-5-carboxylate reductase 1; P5C; P5CR; PRO3; PYCR; PIG45; PP222; ARCL2B; PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial; P5CR 1; P5C reductase 1; proliferation-inducing protein 45; EC 1.5.1.2 |
Gene ID : | 5831 |
mRNA Refseq : | NM_006907 |
Protein Refseq : | NP_008838 |
MIM : | 179035 |
UniProt ID : | P32322 |
Chromosome Location : | 17q25.3 |
Function : | binding; oxidoreductase activity; pyrroline-5-carboxylate reductase activity |
Products Types
◆ Recombinant Protein | ||
PYCR1-3536R | Recombinant Rhesus Macaque PYCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCR1-3175H | Recombinant Human PYCR1 Protein, MYC/DDK-tagged | +Inquiry |
Pycr1-5270M | Recombinant Mouse Pycr1 Protein, Myc/DDK-tagged | +Inquiry |
PYCR1-1815H | Recombinant Human PYCR1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PYCR1-31271TH | Active Recombinant Human PYCR1 protein, His-tagged, Bioactivity Validated. | +Inquiry |
◆ Lysates | ||
PYCR1-1448HCL | Recombinant Human PYCR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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