"PYCR1" Related Products

Expand
Expand

Recombinant Human Pyrroline-5-carboxylate Reductase 1, His-tagged

Cat. No.: PYCR1-935H
Product Overview: Recombinant human PYCR1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography.MW = 35.5 kDa(339aa).
Description: PYCR1 is a universal housekeeping enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. It forms a homopolymer and localizes to the mitochondrion. Defects in PYCR1 are the cause of cutis laxa autosomal recessive type 2B (ARCL2B).
Source: E.coli.
Form: Liquid. In 20 mM Tris-HCl Buffer (pH 8.5) containing 10% Glycerol.
Purity: > 90% by SDS - PAGE.
Concentration: 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSVGFIGAGQ LAFALAKGFT AAGVLAAHKI MAS SPDMDLA TVSALRKMGV KLTPHNKETV QHSDVLFLAVKPHIIPFILD EIGADIEDRH IVVSC AAGVT ISSIEKKLSA FRPAPRVIRC MTNTPVVVRE GATVYATGTH AQV EDGRLME QLLSSVGFCTEVEEDLIDAV TGLSGSGPAY AFTALDALAD GGVK MGLPRR LAVRLGAQAL LGAAKMLLHS EQHPGQLKDN VSSPGGATIH ALHVL ESG GFRSLLINAVEA SCIRTRELQS MADQEQVSPA AIKKTILDKV KLDSPAGTAL SPS GHTKLLP RSLAPAGKD.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Arginine and proline metabolism; Metabolic pathways; Metabolism of amino acids and derivatives
Gene Name: PYCR1 pyrroline-5-carboxylate reductase 1 [ Homo sapiens ]
Synonyms: pyrroline-5-carboxylate reductase 1; P5C; P5CR; PRO3; PYCR; PIG45; PP222; ARCL2B; PYCR1; pyrroline-5-carboxylate reductase 1, mitochondrial; P5CR 1; P5C reductase 1; proliferation-inducing protein 45; EC 1.5.1.2
Gene ID: 5831
mRNA Refseq: NM_006907
Protein Refseq: NP_008838
MIM: 179035
UniProt ID: P32322
Chromosome Location: 17q25.3
Function: binding; oxidoreductase activity; pyrroline-5-carboxylate reductase activity

Online Inquiry

Note: There will be extra charge for optional service!
Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information


Price does not include shipping and packaging costs.Request quote for final price.

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.