Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse Grn protein, His-tagged

Cat.No. : Grn-3287M
Product Overview : Recombinant Mouse Grn protein(NP_032201.2)(Met1-Leu589), fused with His tag, was expressed in HEK293.
Unit
Price
Qty
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Mass : The secreted recombinant mouse Progranulin comprises 583 amino acids and has a predicted molecular mass of 63 kDa. As a result of glycosylation, the apparent molecular mass of rmGRN is approximately 70-90 kDa in SDS-PAGE under reducing conditions.
Proteinlength : Met1-Leu589
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 90 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Grn granulin [ Mus musculus ]
Official Symbol : Grn
Synonyms : GRN; granulin; granulins; PEPI; PCDGF; progranulin; acrogranulin; proepithelin; PC cell-derived growth factor; epithelin;
Gene ID : 14824
mRNA Refseq : NM_008175
Protein Refseq : NP_032201

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (6)

Ask a question
Are there have any relationship between GRN protein and TDP-43 protein? 11/04/2019

There is an interaction between GRN protein and TDP-43 protein, and together they are involved in the development of neurodegenerative diseases.

Why does GRN protein play a role in neuroprotection? 07/21/2019

GRN protein is involved in neuroprotection by regulating cell survival, apoptosis, inflammatory response and other pathways. It may work by promoting neuronal survival, suppressing inflammatory responses, and more.

What is the diagnostic significance of GRN protein in neurodegenerative diseases? 06/17/2019

Abnormal expression of GRN protein is related to neurodegenerative diseases, and detecting the expression level of GRN protein or gene mutation can help diagnose these diseases and provide reference for treatment and prognosis assessment.

What is the role of GRN protein in Alzheimer's disease? 05/05/2019

The role of GRN protein in Alzheimer's disease is not fully understood, but studies have shown that it is involved in the metabolism and clearance of β-amyloid, which may have an important impact on the pathological process.

Are there transcription factors involved in the regulation of GRN protein expression? 02/26/2019

Yes, some transcription factors have been found to regulate the expression of GRN proteins, including CREB, SMAD, etc.

Which role of GRN protein in prefrontal dementia? 02/08/2019

GRN protein plays an important role in prefrontal dementia. It is involved in the survival and maintenance of nerve cells, and its deletion or mutation may lead to degenerative loss of nerve cells.

Customer Reviews (3)

Write a review
Reviews
06/16/2022

    The outstanding quality of proteins lies in their strong biological activity and their high purity during production, which is really rare.

    04/30/2022

      Application of this protein enables researchers to conduct research in more fields and broadens the horizon of scientific research.

      06/29/2019

        This protein has a short half-life, high clearance rate, and high safety and efficacy.

        Ask a Question for All Grn Products

        Required fields are marked with *

        My Review for All Grn Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends