"MAPK8" Related Products

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Recombinant Human MAPK8, GST tagged

Cat.No. : MAPK8-781H
Product Overview : Recombinant Human MAPK8 full length (NP_620637.1) (Met 1-Arg 427), fused with the GST tag at the N-terminus, was produced in Baculovirus-Insect cells.
Source : Baculovirus-Insect Cells
Species : Human
Tag : GST
Form : Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0, 25% glycerol
Molecular Mass : The recombinant human MAPK8/GST chimera consists of 652 amino acids and predicts a molecular mass of 75 kDa. It migrates as an approximately 65 kDa band in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Stability : Samples are stable for up to twelve months from date of receipt at -70ºC.
Storage : Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Gene Name : MAPK8 mitogen-activated protein kinase 8 [ Homo sapiens ]
Official Symbol : MAPK8
Synonyms : MAPK8; mitogen-activated protein kinase 8; PRKM8; JNK; JNK1; JUN N terminal kinase; SAPK1; MAP kinase 8; JUN N-terminal kinase; c-Jun N-terminal kinase 1; stress-activated protein kinase 1; stress-activated protein kinase 1c; mitogen-activated protein kinase 8 isoform JNK1 beta2; mitogen-activated protein kinase 8 isoform JNK1 alpha1; JNK-46; JNK1A2; SAPK1c; JNK21B1/2;
Gene ID : 5599
mRNA Refseq : NM_002750
Protein Refseq : NP_002741
MIM : 601158
UniProt ID : P45983
Chromosome Location : 10q11
Pathway : ATF-2 transcription factor network, organism-specific biosystem; Activated TLR4 signalling, organism-specific biosystem; Activation of BH3-only proteins, organism-specific biosystem; Activation of BIM and translocation to mitochondria, organism-specific biosystem; Activation of BMF and translocation to mitochondria, organism-specific biosystem; Activation of the AP-1 family of transcription factors, organism-specific biosystem; Adipocytokine signaling pathway, organism-specific biosystem;
Function : ATP binding; JUN kinase activity; MAP kinase activity; histone deacetylase binding; histone deacetylase regulator activity; nucleotide binding; protein binding; protein serine/threonine kinase activity; protein serine/threonine kinase activity;

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