"MAPRE1" Related Products

Expand
Expand

Recombinant Human MAPRE1, His-tagged

Cat. No.: MAPRE1-3376H
Product Overview: Recombinant human MAPRE1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. MW = 32.2 kDa (288aa).
Description: MAPRE1, also known as EB1, belongs to the intermediate/early gene family. This protein first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. It localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. MAPRE1 is involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes.
Source: E.coli.
Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol 2mM DTT, 0.1M NaCl.
Purity: > 90% by SDS - PAGE.
Concentration: 0.5 mg/ml (determined by Bradford assay).
Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MAVNVYSTSV TSDNLSRHDM LAWINESLQL NLTKIEQLCS GAAYCQFMDM LFPGSIALKK VKFQAKLEHE YIQNFKILQA GFKRMGVDKI IPVDKLVKGK FQDNFEFVQW FKKFFDANYD GKDYDPVAAR QGQETAVAPS LVAPALNKPK KPLTSSSAAP QRPISTQRTA AAPKAGPGVV RKNPGVGNGD DEAAELMQQV NVLKLTVEDL EKERDFYFGK LRNIELICQE NEGENDPVLQ RIVDILYATD EGFVIPDEGG PQEEQEEY.
Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Pathways: Cell Cycle, Mitotic; DNA Replication
Gene Name: MAPRE1 microtubule-associated protein, RP/EB family, member 1 [ Homo sapiens ]
Synonyms: microtubule-associated protein, RP/EB family, member 1; EB1; MGC117374; MGC129946; MAPRE1; microtubule-associated protein RP/EB family member 1; end-binding protein 1; APC-binding protein EB1; adenomatous polyposis coli-binding protein EB1; End-binding protein 1
Gene ID: 22919
mRNA Refseq: NM_012325
Protein Refseq: NP_036457
MIM: 603108
UniProt ID: Q15691
Chromosome Location: 20q11.1-q11.23
Function: microtubule plus-end binding; protein C-terminus binding; protein binding

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.